The album also features bold Spanish versions of classics. Break It All by Los Shakers becomes Rompan todo, with the collaboration of Sandro. On the other hand, God Only Knows by The Beach Boys is reinterpreted as Solo Dios sabe. The sonic richness is expanded with special guests: Alfredo Alcón recites biblical texts in Treinta denarios, while Jorge Luz contributes his voice in Cucamonga dance. Charly's lyrics for this album are largely introspective, reflecting his personal experiences and feelings. Vampiro, for example, is built on a fragment of a previous song, seeking to capture the musician's perspective upon leaving his first addiction treatment, a message directed at loved ones or followers.
Originally, the idea was considered for this project to be a trio, including Gustavo Cerati. In 1988, Charly García had contacted him to record an album together, which would be called Tango 3. However, Cerati's commitments with Soda Stereo, who were immersed in recording their successful album Canción Animal, coupled with Pedro Aznar's tours with the Pat Metheny Group and the intensity the project required, prevented this collaboration from materializing. Tango 4 was released with a considerable promotional campaign and had a good commercial response, although it did not have an official live presentation. Shortly after its release, the reunion of Serú Girán was already being planned.