The impact of 1999 was immediate. The album's title track, 1999, initially released as the first single, had a modest performance at first, but after the success of Little Red Corvette, which climbed to sixth place on the Billboard Hot 100, the main track was re-released and reached 12th place, consolidating itself as one of his most recognizable compositions. Delirious also broke into the top ten of the Billboard Hot 100, reaching number eight. Additionally, International Lover received a Grammy nomination, marking the first for Prince in the category of Best R&B Vocal Performance by a Male.
The impact of 1999 transcended the charts. The intense rotation of the videos for 1999 and Little Red Corvette on MTV made him one of the first Black artists to have a prominent presence on the channel. Publications like Rolling Stone have included it in lists of the most influential albums, noting how its synthesizer and drum machine arrangements codified the Minneapolis sound. In 2008, the album was inducted into the Grammy Hall of Fame. Following Prince's passing in 2016, 1999 returned to the Billboard 200, surpassing its original position. A 2019 reissue added 35 unreleased recordings, further expanding the legacy of this work.